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María Florencia Acutain

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Open access Oct 2026

Hippocampal GluN2A knockdown differentially alters spatial exploration and behavioral performance in male and female rats

An AAV-mediated shRNA knockdown of GluN2A (GluN2A-kd) targeted to the hippocampus in adult Wistar rats is developed, avoiding developmental confounds and enabling the specific assessment of GluN2A function in mature neurons, position GluN2A as a key modulator of the precision and flexibility of spatial behavior require...

María Florencia Acutain, Fernanda Mariana Silva, L. Castellari et al. · 0 citations

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