Open access
Jul 2026
Synthesis and Biological Activity of Novel Aromatic Aminopropyl Lactams in Two Cancer Cell Models
A one‐pot synthesis of aromatic aminopropyl lactams (ArAPLs) via hydrolysis of bicyclic amidines (DBN, DBU), followed by reductive amination with aromatic aldehydes supports the cytotoxic potential of ArAPLs.
M. Martins, Ruben Valente, Ruben Amaro et al.
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