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Marian Sobhy Azer

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Open access Sep 2026

Propolis-Based Microneedles Incorporating Neratinib-Loaded Ocimum basilicum Essential Oil-Based Lipid Nanovesicles for Minimally Invasive Cancer Therapy: Formulation and In Vivo Evaluation in an Ehrlich Solid Tumor Model

Background: Neratinib (NTB) is a potent pan-HER inhibitor, but its oral bioavailability is limited due to poor aqueous solubility, low permeability, and gastrointestinal toxicity. This study incorporated a bioactive transdermal system by incorporating NTB-loaded nanovesicles of Ocimum basilicum oil (NTB-OOs) into disso...

S. F. Elhabal, Suzan Awad AbdelGhany Morsy, Marian Sobhy Azer et al. · 0 citations

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