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Mariane Vedovatti Monfardini Sagrillo

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Open access Sep 2026

Antigenic remodeling of the SARS-CoV-2 Spike N-terminal domain links sequence variability to structural reorganization of a neutralizing antibody supersite

Introduction The N-terminal domain (NTD) of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike harbors a neutralizing antibody supersite and is a recurrent site of antigenic change. However, how sequence variability across pre- and post-vaccination immune landscapes reshapes antibody recognition rem...

J. S. Ardisson, Brena Ramos Athaydes, Mariane Vedovatti Monfardini Sagrillo et al. · 0 citations

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