Review
Open access
Sep 2026
SIRENA protocol: an Italian, prospective, multicentre cohort study of children and adults with islet autoimmunity and early-stage type 1 diabetes
Abstract Introduction Type 1 diabetes (T1D) is a progressive autoimmune disease with identifiable presymptomatic stages. Islet autoantibody screening, expanded in Italy by Law 130/2023, identifies children and adults at high risk of progression. Structured longitudinal follow-up is needed to characterise disease trajec...
V. Cherubini, R. Gesuita, E. Mozzillo et al.
· BMJ Open · 0 citations