Author

Mariangela Rosa

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Open access Aug 2026

Soft cationic hydrogels based on short peptide sequences for potential localized siRNA delivery

Localized gene-delivery systems represent a key enabling technology for regenerative medicine, diagnostics, and real-time monitoring of biological processes. Among biomaterial platforms, peptide-based hydrogels have attracted significant interest due to their biocompatibility, structural tunability, and ability to...

Luca Cimmino, Mariantonietta Pizzella, Mariangela Rosa et al. · Scientific Reports · 0 citations

Open access Aug 2026

Hydrogels and nanogels based on 2Nap-capped cationic tripeptides: influence of lysine position and siRNA delivery properties.

It is demonstrated that lysine-modified tripeptide NGs are safe and effective tools for gene-silencing applications, and designed to load siRNA via electrostatic interactions.

Mariangela Rosa, Fin Hallam Stewart, C. Diaferia et al. · Biomaterials Science · 0 citations