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Author

Mariia Mikhova

2 papers indexed here

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Open access Sep 2026

Tandem-Affinity Crosslinking Mass Spectrometry Supports a Model of a DNA-PKcs-PP6 Regulatory Complex.

Protein complexes can be modeled with data arising from crosslinking mass spectrometry, but it is difficult to collect such data from cellular sources, particularly for proteins that are part of extensive interaction networks. Here, we present a tandem-affinity purification crosslinking mass spectrometry (xTAP‑MS) meth...

Danny Laurent, Morgan F. Khan, Morgan Hepburn et al. · 0 citations
Open access Sep 2026

Dynamic chromatin tethering of MDC1 regulates genome stability

Abstract DNA double-strand breaks (DSBs) are highly cytotoxic DNA lesions because they disrupt the connectivity of the DNA strand. Homologous recombination (HR) is a high-fidelity DSB repair pathway that copies the sequence spanning the break from a homologous template, but how DNA ends are held together during HR rema...

Joshua R. Heyza, Mariia Mikhova, Cody Phillips et al. · 0 citations

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