A Pediatric Case Series of Autoimmune Lymphoproliferative Syndrome (ALPS): A Single-Center Experience
Autoimmune lymphoproliferative syndrome (ALPS) is an inborn error of immune dysregulation. A defect in lymphocyte apoptosis leads to their accumulation and the survival of autoreactive B lymphocytes. Main characteristics of the disease are lymphoproliferation (lymphadenopathy and/or organomegaly) and autoimmunity (...