Marimuthu Citartan

Structure-Guided Optimization of a LipL32-Targeting DNA Aptamer through Molecular Dynamics and Free-Energy Analysis

Accurate detection of leptospirosis requires high-affinity recognition of the conserved LipL32 biomarker. Although LipL32-targeting DNA aptamers have been identified through systematic evolution of ligands by exponential enrichment (SELEX), the molecular basis of their target recognition remains unclear, limiting rat...

Identification and differential expression analysis of Hfq-bound novel small RNAs in Serratia marcescens by nitrocellulose-based partitioning

Navigating iNOS-targeted molecular imaging for inflammation: from comparative analysis of the current state of molecular imaging and translational challenges to future strategies and prospects

The mechanisms of iNOS in inflammation, strategies for targeting iNOS, and approaches for improving iNOS tracers are described, and an outline of the various imaging technologies, including positron emission tomography (PET), single-photon emission computed tomography (SPECT), fluorescence imaging and magnetic resonanc...

Aptamer-based biosensors for the diagnostics of infectious disease-causing bacteria using spiked and clinical samples: A systematic review.

A systematic review on various biosensors harnessed for the diagnosis of bacteria, which were performed using spiked and clinical samples between 2018 and 2026, shows immense prospects for the diagnostics of pathogenic bacteria.