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Mark S. Freedman

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Open access Sep 2026

Effect of mesenchymal stem cells on peripheral immune cells in multiple sclerosis: results from an international phase 2 clinical trial.

INTRODUCTION The MESEMS trial was a randomized, double-blind, Placebo (Pbo)-controlled, crossover phase 2 study evaluating the safety and efficacy of autologous mesenchymal stromal cells (MSC) in multiple sclerosis (MS). Although the trial did not demonstrate a significant effect on MRI disease activity, MSC may exert...

I. Schiavetti, Mark S. Freedman, S. Thebault et al. · 0 citations

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