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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Mark T. Heise

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Open access Sep 2026

The nucleoside analog CMX521 inhibits coronavirus RNA-dependent RNA polymerase via a two-pronged mechanism.

These findings establish a two-pronged mode of coronavirus polymerase inhibition by CMX521, and suggest a second inhibitory mechanism for CMX521 when the coronavirus polymerase is associated with the viral helicase.

Asif Rakib, Calvin J. Gordon, Thomas K. Anderson et al. · 0 citations

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