Review
Open access
Sep 2026
Targeting MicroRNA-21 in Chronic Kidney Disease: Lessons from the Lademirsen Story
MicroRNA-21 (miR-21) has long been regarded as one of the most promising molecular targets in chronic kidney disease (CKD) because of its consistent upregulation across diverse renal disorders and its involvement in fibrosis, inflammation, oxidative stress, and metabolic dysfunction. Strong preclinical evidence demonst...
V. Popović, Aleksandar Sič, Selena Gajić et al.
· Medical Science · 0 citations