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Author

Marko Hanževački

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Open access Sep 2026

Redox Control of S-sulfocysteine Formation in Adenosine Phosphosulfate Reductase

Sulfur assimilation fuels bacterial growth by supplying the reduced sulfur required for the biosynthesis of sulfur-containing biomolecules. Adenosine 5′-phosphosulfate reductase (APSR) catalyzes the first reductive step of this pathway, converting adenosine 5′-phosphosulfate (APS) to adenosine monophosphate. This react...

Matilda Ymeraj, Carlos A. Ramos-Guzmán, Marko Hanževački et al. · 0 citations
Open access Oct 2026

Hydration Changes are Essential for Efficient Breakdown of Faropenem by the L1 Metallo-β-lactamase

Metallo-β-lactamases (MBLs) are key contributors to antimicrobial resistance (AMR). The L1 MBL, originally from Stenotrophomonas maltophilia, is a tetrameric, dizinc, subclass B3 MBL that efficiently hydrolyzes most β-lactam antibiotics and evades inhibitors that act on other MBLs. Using quantum mechanics/molecular m...

Papu Kalita, Carlos A. Ramos-Guzmán, Marko Hanževački et al. · 0 citations

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