Regulatory T cells (Tregs) are essential for immune tolerance and tissue homeostasis. Their dysfunction contributes to a broad range of autoimmune, inflammatory, and degenerative diseases, motivating interest in Treg-based therapies. Clinical translation has been constrained by limited stability, persistence, and funct...
N. Zammit, Martina Sassone-Corsi, P. Zarin et al.· Frontiers in Immunology· 0 citations
Analysis of transcriptomic and flow cytometry analyses and a novel hypoimmune approach improves allogeneic cell persistence by preventing T, B, and NK cell mediated rejection support EngTregs as a potent, stable, and versatile cell therapy platform for autoimmune, inflammatory, and ischemic diseases.
P. Zarin, Gene I. Uenishi, Martina Sassone-Corsi et al.· Journal of Immunology· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.