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Author

Markus Barden

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Review Open access Sep 2026

CAR T cell cancer immunotherapy: who does the job?

This review reframe CAR T cell therapy as the induction of a multi-system immune response rather than a uni-directional cytotoxic cell-autonomous intervention, and proposes that a calibrated, broad immune cell activation should be viewed as design principle for next-generation CAR T cell therapies.

D. Harrer, Markus Barden, H. Abken · 0 citations
Review Open access Aug 2026

In vivo CAR T cells on the highway: a roadmap for the next decade

Although still in its infancy, in vivo genetic engineering shows promise for CAR T cell therapy in a wide range of cancer patients and has the potential to reprogram patients’ immunity in autoimmunity, chronic infections, and regenerative medicine.

Markus Barden, D. Harrer, Hinrich Abken · 0 citations

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