A novel supercritical fluid chromatography - evaporative light scattering detection method for the quantification of paraconic acids in European Cetraria islandica (Iceland moss) samples.
Paraconic acids are bioactive constituents of Iceland moss, a medicinal drug widely used to relieve coughs. They are characterized by high lipophilicity and a γ-butyrolactone ring system but lack strong UV-vis chromophores. Consequently, LC-DAD, despite remaining one of the most widely used analytical techniques in nat...