Author

Marla E. Tharp

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Open access Sep 2026

α-Synuclein Seeding in Dopaminergic Neurons Transplanted into the Putamen of Parkinson’s Disease Patients

Healthy embryonic neurons grafted into the putamen of Parkinson’s disease (PD) patients start to develop Lewy pathology 10 years after transplantation. It remains unclear whether this pathology is initiated by the spread of host-derived α-synuclein (αsyn) aggregates which seed aggregation in the grafted cells or arises...

Jayda B. Duvernay, B. Killinger, Solji G. Choi et al. · bioRxiv · 0 citations

Review Open access Oct 2026

The AIMS Clinic Model: A Retrospective Analysis of Interdisciplinary Movement-Neuropalliative Care for People With Late-Stage Parkinsonism.

BACKGROUND AND OBJECTIVES Patients with late-stage parkinsonism face complex, progressive symptoms requiring specialized interdisciplinary care, yet the unique needs of these patients and family care partners are often inadequately addressed in standard neurology practice. Evidence supporting innovative palliative care...

M. Husain, Angela Hong, Marla E. Tharp et al. · Neurology Clinical Practice · 0 citations