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Marla Popov

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Open access Sep 2026

Absolute and Relative Quantification of Glycation on Biotherapeutic IgGs Using Heavy Isotope–Labeled Proteins

Post-translational modifications (PTMs), such as glycation, can be introduced during the manufacturing and storage of therapeutic proteins, including monoclonal antibodies (mAbs). Glycation modification may alter the safety and efficacy of therapeutic drugs, thus necessitating their accurate quantification. Relative qu...

S. Priya, Marla Popov, Ron Orlando · 0 citations

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