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Marnix M. Medema

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Review Open access Oct 2026

Role of the urobiome in urinary tract infections: current knowledge and research prospects.

Urinary tract infections (UTIs), particularly cystitis, are among the most common bacterial infections worldwide, with a disproportionate burden on adult female individuals, who often have recurrence. The discovery of the urobiome, a low microbial biomass community in the urinary tract, has transformed our understandin...

Marleen D. Hekker, Adam J. Bindas, Freya Darling Eriksen et al. · 0 citations
Review Open access Sep 2026

Integrating multi-omics technologies to decipher microbiome functions

This perspective highlights recent advances in multi-omics microbiome research, outlines key obstacles in data integration and metadata harmonization, and proposes a collaborative roadmap for scalable, FAIR-compliant multi-omics investigations and potentially disruptive Artificial Intelligence advances.

T. Van Den Bossche, Eunice Lazau, Velma T. E. Aho et al. · 0 citations
Open access Aug 2026

Elucidating biosynthetic pathways related to the synthesis of small halogenated peptidic natural products in marine sponge microbiomes

The present work queried metagenomes of several sponge species by making use of a minimal set of core enzymes that postulate to be necessary to produce small peptidic NPs, revealing a variety of novel BGC architectures, many of which showed conservation among sponge host phylogenies and were encoded in the genomes of d...

Catarina Loureiro, M. Schorn, Mohammad M. Alanjary et al. · 0 citations

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