Database Mining Reveals Distinct Clusters of Putative Diphthamide-Specific Mono-ADP-Ribosylating Toxins in Vibrio and Aeromonas
Diphthamide-specific mono-ADP-ribosylating toxins form a structurally conserved but phylogenetically diverse family of AB-type bacterial toxins, with Pseudomonas exotoxin A (PE) serving as a prototypical member. Here, we expand the known diversity of PE-like toxins (PLTs) through comprehensive genome mining and phyloge...