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Author

Marta R. Storl-Desmond

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2 papers indexed here

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Sep 2026

Abstract A019: Tumor Nutrient Stress Regulates Cancer-associated Fibroblast Heterogeneity

Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer type with a 5-year survival rate of only 13%. PDAC is unique in that up to 90% of the tumor bulk is comprised of a dense desmoplastic stroma. Enriched within PDAC’s extensive stroma are cancer-associated fibroblasts (CAFs). CAFs orchestrate tumor progression...

Marta R. Storl-Desmond, Nicole Liu, K. Forti et al. · 0 citations
Sep 2026

Abstract A013: Tumor microenvironmental metabolites regulate cancer-associated fibroblast heterogeneity

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a prominent desmoplastic response with a high abundance of cancer-associated fibroblasts (CAFs). CAFs are a functionally and transcriptionally heterogeneous population of cells and include inflammatory CAFs (iCAFs), thought to promote tumor growth via the se...

Simon Schwoerer, Chu-Fan Cai, Jessica Stradley et al. · 0 citations

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