Open access
Jul 2026
Observation of Mechanical and Kinetic Distinctions between Individual Isoleucine and Arginine Residues in a Peptide Dissociating from a Model Lipid Bilayer
The data reveal that both the mechanics and kinetics of peptide detachment are sensitive to the identity and sequence position of individual residues, highlighting the power of integrating CG MD and single-molecule force spectroscopy to unravel residue-specific, sequence-dependent factors underlying peptide–lipid interactions.
Ryan S. Smith, Krishna P Sigdel, D. R. Weaver et al.
· Langmuir · 0 citations