Engineering Klebsiella oxytoca for enhanced 2,3-butanediol production from gluconate
Historically, microbial production of 2,3-BD has relied predominantly on glucose as the substrate. However, its fermentation necessitates microaerobic conditions due to inherent redox imbalances. This limitation complicates process control and can lead to undesirable late-stage consumption of 2,3-BD. This study...