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Martina Janoušková

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Open access Aug 2026

Transcriptional Regulator FabR Is Associated with the Virulence of Non-typeable Haemophilus influenzae in Host-Pathogen Interactions.

Deletion of fabR reduced host cell adherence, increased serum sensitivity, enhanced IgG deposition, and decreased vitronectin binding compared with the wild-type strain, and ΔfabR mutants from multiple NTHi strains showed increased metabolic activity, indicating a conserved role for FabR in metabolic regulation.

Martina Janoušková, Yu-Ching Su, Sandra Jonsson et al. · Journal of Infectious Diseas... · 0 citations