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Author

Martina Lepore Signorile

2 papers indexed here

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Open access Sep 2026

p38α Signaling Is Associated with Pancreatic Ductal Adenocarcinoma Progression and Represents a Potential Therapeutic Vulnerability

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, and approximately 15% of cases arise from intraductal papillary mucinous neoplasms (IPMNs). These precursor lesions can progress to invasive cancer through the accumulation of molecular alterations. To identify pathways associated with this...

I. Grassi, Elisabetta Di Nicola, Erica Candela et al. · 0 citations
Open access Sep 2026

Targeting the DNA-repair chromatin-modifier protein SMYD3 as a novel epigenetics-based therapy for gastric cancer

SMYD3 is a histone methyltransferase implicated in cancer progression and is overexpressed in several malignancies, including gastric cancer (GC). Building on previous evidence linking SMYD3 to DNA damage repair, we investigated the molecular mechanisms through which SMYD3 regulates double-strand break (DSB) repair in...

Katia De Marco, Marialaura Latrofa, G. Forte et al. · 0 citations

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