2026
Experimental strategies for evaluating the impact of HDACs and HDAC inhibitors on the epigenome. ChiP-seq.
Martina Minisini, Alessio Bertozzo, Eros Di Giorgio et al.
· Methods in Enzymology · 0 citations
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Open access
Jul 2026
Targeting the NuRD Component, CHD4, Impairs Foxp3+ Treg Cell Production and Function and Promotes Anti-Tumor Immunity
CHD4 is identified as a critical epigenetic regulator of Treg lineage stability and pharmacological targeting of the CHD4/NuRD axis is established as a promising strategy to selectively disrupt tumor-associated Tregs and enhance antitumor immunity.
Yan Xiong, Li-Qing Wang, Martina Minisini et al.
· bioRxiv · 0 citations