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Author

Martina Rudelius

2 papers indexed here

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Open access Sep 2026

Single-Cell Profiling Links T-Cell Accumulation and TH2/TH17 Dynamics to Eosinophilic Esophagitis (EoE) Activity in Children.

BACKGROUND According to current guidelines, disease activity in eosinophilic esophagitis (EoE) is measured based on eosinophil infiltration in the esophageal tissue. To investigate the functional role of non-eosinophilic immune cells, we examined immune cell infiltrate over the disease course in pediatric patients with...

Hannes Hoelz, M. Warkotsch, Simon Buehler et al. · 0 citations
Open access Oct 2026

Targeting CD28 on T lineage malignancies with chimeric antigen receptor T cells

Currently, no immunotherapy is approved for T cell acute lymphoblastic leukemia (T‑ALL). High initial response rates to CD7‑directed chimeric antigen receptor (CAR) T cells are limited by profound T cell aplasia and CD7‑negative immune escape, underscoring the need for alternative targets. Here, we show that CD28 is ov...

Semjon Willier, Julian Färber, Theodora Ispyrlidou et al. · 0 citations

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