Plexiform neurofibromas (PNs) are among the most complex and challenging manifestations of neurofibromatosis type 1 (NF1). Recent advances in understanding their epidemiology, natural history, biology, and imaging features, together with the introduction of MEK inhibitors, have significantly reshaped clinical managemen...
C. Santoro, E. Arkhangelskaya, Ambra Bonvicino et al.· Neurological Sciences· 0 citations
Highlights What are the main findings? This systematic review summarizes the currently available evidence on the clinical, neuroradiological, cerebrospinal fluid, treatment, and outcome characteristics reported in pediatric CLIPPERS. The available evidence suggests that pediatric CLIPPERS may present with neuroimaging...