Review
Open access
Sep 2026
Obesity, Insulin Resistance and Type 2 Diabetes Mellitus - Pathophysiological Mechanisms and Exercise-Based Strategies
Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder characterized by chronic hyperglycemia resulting from insulin resistance and progressive pancreatic β-cell dysfunction. Its pathogenesis involves multiple interconnected mechanisms affecting skeletal muscle, liver, adipose tissue, and systemic metabolic re...
Joanna Jędrysiak, Greta Stołecka, Paulina Głodzik et al.
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