Toll-Like Receptors 2 and 4, Nitric Oxide, and Myeloid Differentiation Primary Response 88 in Women Infected with Toxoplasma Gondii
Background: The host resistance to Toxoplasma gondii is initiated by innate recognition of Toll-like receptors (TLRs), which reach the adaptor myeloid differentiation primary response 88 (MyD88) to drive interferon-γ (IFN-y)-dependent nitric oxide (NO) production. Human studies of the integration of these mediators...