Mary G. Ardren

Recruitment of Aα/Aβ fibers during tonic electrical, optogenetic and combined stimulation in the mouse sciatic nerve

Neuromodulation of peripheral nerves via implanted devices produces relief from chronic pain in some patients, but rarely fully eliminates pain. Electrical stimulation lacks selectivity (e.g., between afferent and efferent fibers) to activate only the target Aα/Aβ-fiber axons and must have the stimulating current...