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Maryam Lotfi

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Open access Jul 2026

Altered expression of ET-1 and HMGB1 together with higher MMP-9 activity in serum-derived exosomes of chronic lymphocytic leukemia.

Findings showed that serum-derived exosomes from CLL patients have higher expression of ET-1 and HMGB1 and higher MMP-9 enzymatic activity, which suggest that exosomal ET-1, HMGB1, and MMP-9 may serve as potential non-invasive biomarkers for disease monitoring and warrant further investigation regarding their biological and clinical significance in CLL.

Maryam Ghotbbahaei, Amirhossein Amoei, Maryam Lotfi et al. · 0 citations