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Proinflammatory activation of macrophages promotes various inflammatory disorders. The molecular mechanisms underlying macrophage activation, particularly in the context of nuclear translocation of proinflammatory response mediators, remain obscure. We have used a systems approach to explore key regulators of macrophag...
Current knowledge on the roles of noncoding RNAs in regulating macrophage function in atherosclerosis and CKD is discussed, with particular emphasis on the molecular mechanisms underlying inflammatory responses and disease progression.
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