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Author

Masayuki Kobayashi

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Review Open access Sep 2026

Replication Stress Tolerance in Adult T-Cell Leukemia

Replication stress (RS) represents a major vulnerability of cancer cells treated with nucleoside analogs and related antimetabolites; however, tumors frequently acquire tolerance mechanisms that permit survival despite persistent DNA lesions. This review examines molecular determinants of RS tolerance, focusing on huma...

Yusuke Okamoto, Masayuki Kobayashi, Takashi Sakamoto et al. · 0 citations

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