L-carnitine attenuates Aβ₁-₄₂-induced spatial cognitive deficits and hippocampal dysfunction in a rat model of Alzheimer's disease.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive dysfunction and impaired synaptic plasticity. This study evaluated whether chronic L-carnitine (LC) attenuates amyloid-beta 1-42 (Aβ₁-₄₂)-induced spatial learning and memory deficits following intracerebroventricular (ICV) A...