Massimiliano Paesani

Physical mechanisms of nanoparticle intracellular release through membrane pore nucleation and expansion

Successful intracellular delivery requires a nanocarrier to adhere to the cell membrane, be wrapped and internalized and finally released into the cytoplasm before it is degraded. While the initial steps have been intensively studied, the intracellular release of a nanocarrier has received comparatively less attention...