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Author

Massimo Bottini

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4 papers indexed here

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Open access Aug 2026

External validation of a machine learning-based web application for personalized testing of objective functioning using the five-repetition sit-to-stand test

Simple generalized thresholds for assessing functional impairment in clinical testing are limited, as they fail to consider patient-specific properties such as age, body height, and body mass index. A previously developed machine learning-based model for personalized testing using the five-repetition sit-to-stand (5R-S...

Kenneth Arockia, Massimo Bottini, A. Klukowska et al. · 0 citations
Open access Oct 2026

A standardized and reproducible pipeline for fast multi-view digitally reconstructed radiograph (DRR) generation

Digitally reconstructed radiographs (DRRs) are synthetic projections derived from computed tomography (CT) data and are increasingly used in 3D synthetic image generation. However, variability in preprocessing and projection frameworks limits reproducibility and comparability across studies. We present a standardized p...

Massimo Bottini, Istiak Khan, Olivier Zanier et al. · 0 citations
Open access Aug 2026

Fully Automated Segmentation of Anatomical Subregions of the Thoracolumbar Spine on Computed Tomography.

Segmentations of the vertebral column that include anatomical subregions can be used for patient education, pedicle screw planning, or radiomic feature extraction for spinal surgery. Deep learning has proven successful in tackling medical image segmentation; therefore, we aim to train a multiclass vertebral subregion s...

Raffaele Da Mutten, Sven Theiler, Massimo Bottini et al. · 0 citations
Review Open access Aug 2026

Evaluation metrics for synthetic medical imaging.

BACKGROUND Advances in generative artificial intelligence (AI) have accelerated the development and application of synthetic medical imaging. Despite this rapid progress, the evaluation of synthetic medical images remains heterogeneous, with numerous metrics proposed to assess fidelity, realism, diversity, and clinical...

D. D. de Wilde, Benjamin Schärli, Kym Ackermann et al. · 0 citations

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