Over the years, many antibiotics have been developed, but most have become less effective due to antimicrobial resistance, especially those targeting enzymatic pathways. This growing resistance poses a serious global health threat. It is now recognized that physically disrupting bacterial cell membranes is less prone...
Diletta Bergamo, Katarina Cirnski, Mathias Müsken et al.· Journal of Medicinal Chemist...· 0 citations
ABSTRACT Pseudomonas aeruginosa is a versatile, opportunistic pathogen, well-known for its adaptability to the challenging conditions encountered during infection of the human host. In chronic biofilm-associated infections, variations in motility and LPS structure are commonly observed adaptive traits. In this study, w...
Oliver Hartmann, Matthias Preusse, Ann Kathrin Heroven et al.· mBio· 0 citations
This work reveals a previously unrecognized mechanism of interdomain hormonal modulation, where a bacterium uses a structurally convergent transporter and vesicular delivery to actively shape host physiology and to improve the symbiotic performance.
Natalia Moreno-de Castro, Mustafa Safa Karagöz, Irene Herrero Gómez et al.· bioRxiv· 0 citations
Detailed genomic, biochemical and physiological analyses revealed a vertical inheritance and long ancestral history of aerobic anoxygenic photosynthesis in Rhizobiaceae rather than multiple recent horizontal transfers, indicating a vertical inheritance and long ancestral history of aerobic anoxygenic photosynthesis in...
Steven B. Kuzyk, Philipp Halama, M. Saini et al.· bioRxiv· 0 citations
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