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Mathieu Reymond

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#artificial intelligence Preprint Aug 2026

Training Chemical Plausibility-Aware Large Language Models for Single-Step Retrosynthesis

This work introduces Top-K prompting as a robust training and inference paradigm to better capture diverse, plausible reaction predictions and establishes Top-K, plausibility-aware training as a practical new direction for robust future LLM-based synthesis planning.

B. Zagribelnyy, Ivan D. Ilin, N. Bondarev et al. · 0 citations