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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Mathilde Roth

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Review Open access Oct 2026

Recent advances in understanding the regulatory mechanisms of P4-ATPase lipid flippases

Abstract P4-ATPases establish and maintain transbilayer lipid asymmetry in eukaryotic membranes by transporting phospholipids from the exoplasmic to the cytosolic membrane leaflet at the expense of ATP hydrolysis. In recent years, biochemical analysis together with an increasing number of cryo-electron microscopy struc...

Pauline Funke, Mathilde Roth, T. Dieudonné et al. · 0 citations
Open access Jul 2026

Mechanistic Insights into Autoinhibition of the Human Flippase ATP8B1

It is demonstrated that a minimal peptide spanning residues 1216-1228, which bridges the A- and N-domains in the autoinhibited conformation, is sufficient to inhibit ATPase activity.

Michelle Juknaviciute Laursen, Mathilde Roth, P. Nissen et al. · 1 citation

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