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Author

Matthew P. Frosch

2 papers indexed here

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Open access Aug 2026

Neuropathologic Features of Adult-Onset Progressive Leukodystrophy Due to KARS Pathogenic Variants

Objectives To report the histopathologic features seen in congenital deafness and adult-onset leukoencephalopathy (DEAPLE) caused by biallelic pathogenic variants in KARS and expand on neuroradiologic features reported in other cases. Methods We present the clinical, neuroimaging, and histopathologic findings of a pati...

A. Nagy, Michael S. Marshall, Matthew P. Frosch et al. · 0 citations
Open access Aug 2026

A public generalizable AI tool for automated segmentation of coronal brain tissue slabs for 3D neuropathology

A deep learning model is presented to automate segmentation of tissue from the background and out-of-slice tissue in photographs, which currently requires laborious manual intervention in postmortem brain tissue analysis.

John Williams-Ramirez, Dina Zemlyanker, Lucas J. Deden-Binder et al. · 0 citations

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