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Author

Matthew R. Gardner

2 papers indexed here

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Open access Sep 2026

T-cell responses shape infant SIV reservoirs and post-intervention control following AAV9-eCD4-Ig and latency reversal.

Early antiretroviral therapy (ART) limits viral reservoir establishment in infants but also constrains viral-specific immunity required to clear reactivated cells. In the early ART context, we evaluated whether combining adeno-associated virus serotype 9 (AAV9)-vectored eCD4-IgG1 with pharmacologic latency reversal usi...

Jairo A. Fonseca, Alexis C. King, Kaleaha S. Davis et al. · 0 citations
Open access Aug 2026

Long-term depletion of KIR3DL01+ NK cells by adeno-associated viral-vectored antibody delivery alters chronic SIV infection

It is suggested that KIR3DL01+ NK cells contribute to the inhibition of SIV replication during chronic infection, and the feasibility of AAV-vectored antibody delivery for long-term, perhaps indefinite depletion of a lymphocyte subset in a nonhuman primate model is demonstrated.

Kjell Sandstrom, Grace N. Hagedorn, Sean C Robinson et al. · 0 citations

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