Author

Matthew Schombs

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Open access Sep 2026

Analytical evaluation of eukaryotic cell-free translation (CFT) systems to assess mRNA translatability

Although HCL translated less protein than either WGE or RRL systems, it showed several advantages, notably a larger linear range and greater sensitivity to mRNA thermal stress and dsRNA impurities.

Benjamin W. Roose, Pankaj Dwivedi, Matthew Schombs · bioRxiv · 0 citations