Oct 2026
Genotype and arrhythmic risk in dilated cardiomyopathy.
K. Padalia, A. Fornaro, B. Claggett et al.
· European Heart Journal · 0 citations
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Sep 2026
Atrial Fibrillation in Genotyped Dilated Cardiomyopathy: Epidemiology, Risk Factors, and Outcomes: Insights From the SHaRe Registry.
BACKGROUND Atrial fibrillation (AF) is the most common arrhythmia in dilated cardiomyopathy (DCM) and is associated with adverse outcomes. However, the genetic determinants of AF risk and its prognostic significance across genotyped DCM subtypes remain unknown. METHODS In this observational cohort study, we analyzed...
I. Balakrishnan, A. Heymans, B. Claggett et al.
· Circulation: Heart Failure · 0 citations
Open access
Jul 2026
Scaled Multidimensional Assays of Variant Effect Identify Sequence-Function Relationships in Hypertrophic Cardiomyopathy
This work provides a platform for extending genome engineering in induced pluripotent stem cells to multiplexed assays of variant effects across diverse disease-relevant cellular phenotypes, enhancing the understanding of variant pathogenicity and uncovering novel biological mechanisms that could inform therapeutic str...
Yuta Yamamoto, Kaiser Chua, David W. Staudt et al.
· Circulation · 0 citations