Matthew V. Tirrell

Macromolecular association creates dispersity of components that determines liquid-liquid phase separation of oppositely charged polyions.

Developing insight into liquid-liquid phase separation in complex polyelectrolyte mixtures has acquired new urgency considering the role this process plays in the formation of biomolecular condensates, which are involved in diverse processes including, stress response, signal transduction, metabolism, gene regulation,...

Mechanosensitive Endothelial METTL7A Regulates Internal m7G mRNA Methylation and Protects Against Atherosclerosis.

Hierarchical and cascading cooperative rearrangement regions in dense colloidal suspensions.

Cooperative dynamics in soft materials such as colloidal suspensions, gels, and polymers stem from complex surface interactions and structural heterogeneities, driving behaviors such as yielding, failure, and avalanches. In X-ray photon correlation spectroscopy (XPCS), these dynamics manifest as localized decorrelation...