Fabrication of Aligned Polycaprolactone Nanofibrillar Bundles to Control Cell-Mediated Collagen Deposition in Engineered Cartilage.
The structural anisotropy of collagen is essential for the function of tissues such as articular cartilage, yet current biofabrication strategies fail to reproduce this hierarchical organization. Melt electrowriting (MEW) is widely used to fabricate mechanically stable polycaprolactone (PCL) scaffolds for reinforcing h...