It is demonstrated that interfacial packing provides a useful structural framework for rationalizing the membrane behavior of closely related amino acid-based surfactants, while highlighting that additional molecular factors are likely to contribute to surfactant–membrane interactions.
D. R. Perinelli, Michele Verboni, Mattia Tiboni et al.· Langmuir· 0 citations
The combination of DOTAP-mediated hydrophobic ion pairing and microfluidic-assisted SLN production represents a potentially promising strategy for improving semaglutide encapsulation, gastrointestinal stability, and epithelial transport, while maintaining a favorable balance between mucus interaction and mucodiffusion.
Ilaria Arduino, R. Iacobazzi, Alessia Pontrelli et al.· International journal of pha...· 0 citations
A dual-drug delivery system co-loading trametinib, MEK inhibitor, and alisertib, Aurora A kinase inhibitor was developed, optimized to maintain a previously established synergistic ratio which effectively overcome acquired resistance to standard-of-care therapies and induce durable tumor regression.
Giulia Lovati, Pietro Milesi, Paolo Fossati et al.· Journal of Controlled Releas...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.