Open access
Aug 2026
Disentangling MRI-derived blood–brain barrier leakage into vascular permeability and surface area
In neurovascular and neurodegenerative diseases, blood–brain barrier (BBB) disruption can be subtle and diffuse, and MRI-derived measures are confounded by microvascular architecture. Therefore, we aimed to disentangle the MRI-derived blood–brain barrier leakage rate (Ki) into intrinsic vascular permeability (P) and su...
Damon Verstappen, J. D. de Jong, P. Voorter et al.
· Journal of Cerebral Blood Fl... · 0 citations