The role of SLC7A11 in regulating breast cancer brain metastasis
SLC7A11 is identified as a non-canonical regulator of ECM/integrin-mediated FAK survival signaling in brain metastatic breast cancer cells, indicating that FAK signaling contributes to BCBM tumor maintenance and that it's inhibition can effectively suppress tumor growth.
Kevin Michael Hughley, Mauricio J. Reginato
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