Max Brenner

Extracellular cold-inducible RNA-binding protein in renal ischemia–reperfusion injury and its progression to chronic kidney disease

Acute kidney injury (AKI) from renal ischemia–reperfusion (IR) injury is a major cause of acute organ dysfunction with significant morbidity and mortality. Critically, up to 50% of AKI survivors progress to chronic kidney disease (CKD), yet the mechanisms driving this maladaptive transition remain incompletely unders...